
The respiratory system is a highly balanced mechanism reliant on humidity. Clinical efficacy is significantly improved by emulating the balance of temperature and humidity that occurs naturally in healthy adult lungs. Bridging the gap between artificial breathing systems and a normally functioning airway ensures greater benefits for the patient and clinician alike.
To provide therapies that maintain optimal lung function it is necessary to understand the physiological balance of humidity in the
normal airway.
Three Key Benefits of Humidification:
1. Assist natural defense mechanisms in the airway.
2. Promote efficient gas exchange and ventilation.
3. Increase patient comfort and tolerance to treatment.
Optimal and Essential Humidity

37 °C, 44 mg/L, 100% Relative Humidity
During normal inspiration, the airway conditions inspired gases with heat and humidity to body temperature, 100% relative humidity with 44 mg/L of absolute humidity. The lungs rely on these optimal states to maintain the physiological balance of heat and moisture necessary for optimized airway defense and gas exchange while maintaining patient comfort.

31 °C, 32 mg/L, 100% Relative Humidity
The use of humidification with noninvasive mask therapies is essential for maintaining the natural balance of heat and moisture in the airways. The level of conditioning required is directed by the amount of humidity produced naturally in the nasopharynx when breathing through the nose.