Dr. Jean-Pierre Frat (MD, PhD) is currently working in the medical ICU at the University Hospital of Poitiers in France. He works within the ALIVE lab working on non-invasive strategies of oxygenation and sleep disorders in ICU patients. He has conducted several multicentre clinical trials in collaboration with the European network REVA assessing the impact of non-invasive respiratory therapies including the landmark FLORALI study. Currently, he is conducting another important clinical trial, the SOHO study which will assess conventional oxygen therapy and NHF in patients with acute hypoxemic respiratory failure.