Physiological Effects

 

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Reduces respiratory rate

Reduces respiratory rate

Reduces carbon dioxide

Reduces carbon dioxide

Improves oxygenation

Improves oxygenation

  • Delivers a prescribed FIO2
    Ritchie et al. Anaesth Intensive Care. 2011,
     
  • Improved oxygenation in patients with respiratory distress
    Peters et al. Respir Care. 2013.
    Sztrymf et al. Intensive Care Medicine. 2011.

  • Improves oxygenation compared with traditional oxygen therapy
    Corley et al. Br J Anaesth. 2011.
    Roca et al. Respir Care. 2010
     
  • Improved oxygenation during bronchoscopy
    Lucangelo et al. Crit Care Res Pract. 2012.

"[Nasal High Flow] significantly reduced respiratory rate."

~ Sztrymf et al. Intensive Care Med. 2011.

Increases tidal volume

Increases tidal volume

  • Increases tidal volume compared with low-flow oxygen therapy
    Corley et al. Br J Anaesth. 2011.

Increases end-expiratory lung volume

Increases end-expiratory lung volume

  • Increases airway pressure, which increases end-expiratory lung volume
    Based on measurements of lung impedance.
    Corley et al. Br J Anaesth. 2011.

Improves mucus clearance

Increases mucus clearance

  • Humidification therapy improves mucocillary clearance
    Hasani et al. Chron Respir Dis. 2008.

Optiflow FAQs, related to physiological outcomes

Who does Nasal High Flow work on?

How much pressure is generated by Nasal High Flow?

What effect does low humidity have on the airway?

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