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Kaplain-Meier analysis of time from extubation to reintubation graph

'Use of NHF reduced the risk of reintubation within 72 hours.'

(among extubated patients at low risk for reintubation)

~ Hernández et al. JAMA. 2016.


 
Reduced 90 day mortality and reduced intubation rate graphs

NHF significantly reduced need for intubation in more acute patients

(compared to standard O2 and NIV,
PaO2:FiO2 ≤ 200 mmHg)

~ Frat et al. New Engl J Med. 2015.
 

Medical staff with Nasal High Flow male patient

NHF was found
non-inferior to BPAP

(among cardiothoracic surgery patients with or at risk for respiratory failure)

~ Stéphan et al. JAMA. 2015

Reduces escalation of care

Pre-intubation: 

  • Significantly reduces intubation rate when PaO2:FiO2 ≤200 mm Hg 
        Frat et al. New Engl
        J Med. 2015.


Post-Extubation:

  • Reduces escalation to non-invasive ventilation and re-intubation
         Parke et al. Respir
         Care. 2011.
         Hernández et al.
         JAMA. 2016. 
 
  • Non-inferior to Bi-level Positive Airway Pressure
         Stéphan et al.
         JAMA. 2015.

Improves symptomatic relief

  • Significantly reduced intensity of respiraotry discomfort and dyspnea
         Frat et al. New Engl J
         Med 2015. 
​  
  • Rapid and sustained improvement of dyspnea in patients with respiratory distress in the emergency department  
         Lenglet et al. 
         Respir Care. 2012. 

Improves patient comfort

  • Well tolerated
          Sztrymf et al. Intensive
          Care Medicine. 2011. 
 
  • Greater overall comfort than face mask
          Roca et al.
          Respir Care.2010. 
          Lenglet et al.
          Respir Care. 2012. 
 


Resources

Optiflow Adult Clinical Paper Summaries

(PDF 0.8MB)

Download

Optiflow Therapy Brochure

(PDF 0.9MB)

Download

Optiflow Flow Matters Newsletter - Issue 8

(PDF 0.1MB)

Download
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