Physiological Effects


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Reduces respiratory rate

Reduces respiratory rate

Reduces carbon dioxide

Reduces carbon dioxide

Improves oxygenation

Improves oxygenation

  • Delivers a prescribed FIO2
    Ritchie et al. Anaesth Intensive Care. 2011,
  • Improved oxygenation in patients with respiratory distress
    Peters et al. Respir Care. 2013.
    Sztrymf et al. Intensive Care Medicine. 2011.

  • Improves oxygenation compared with traditional oxygen therapy
    Corley et al. Br J Anaesth. 2011.
    Roca et al. Respir Care. 2010

  • Improved oxygenation during bronchoscopy
    Lucangelo et al. Crit Care Res Pract. 2012.

"[Nasal High Flow] significantly reduced respiratory rate."

~ Sztrymf et al. Intensive Care Med. 2011.

Increases tidal volume

Increases tidal volume

  • Increases tidal volume compared with low-flow oxygen therapy
    Corley et al. Br J Anaesth. 2011.

Increases end-expiratory lung volume

Increases end-expiratory lung volume

  • Increases airway pressure, which increases end-expiratory lung volume
    Based on measurements of lung impedance.
    Corley et al. Br J Anaesth. 2011.

Improves mucus clearance

Increases mucus clearance

  • Humidification therapy improves mucocillary clearance
    Hasani et al. Chron Respir Dis. 2008.
Take me to FAQs


Optiflow Adult Clinical Paper Summaries

(PDF 0.8MB)


Optiflow Flow Matters Newsletter - Issue 8

(PDF 0.1MB)


Optiflow Therapy Brochure

(PDF 0.9MB)



Optiflow Nasal High Flow



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