The early use of NHF is associated with improved physiological and clinical outcomes compared to standard oxygen therapy, including1-6:
Clinical evidence supports a dose-by-weight approach with suggested flow rates of approximately 2 liters per kilogram per minute (L/kg/min) for infants between 3.0 and 12.5 kilograms.4,7-12
However, there is no evidence to support this practice for preterm neonates, older children or adults. Published clinical protocols may give guidance to setting flow rates in children.7-12 The graphic below summarizes the findings from published literature.
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