OptiflowTM nasal high flow therapy

Proven respiratory support
 What is NHF?     Who is NHF for? 

While many terms (e.g. HFNC, high flow oxygen) describe nasal high flow therapy, one stands out. Optiflow nasal high flow therapy. 

Optiflow nasal high flow delivers respiratory support to your patients, by providing heated, humidified air and oxygen at flow rates up to 70 L/min through the unique Optiflow nasal cannula and delivered by a device such as the Airvo 2 nasal high flow system.  

Accelerate your understanding of high flow therapy 

If you’re new to high flow therapy, training others, or want a quick refresher, follow this learning plan to accelerate your knowledge.


Optiflow™ Nasal High Flow in the Emergency Department

Reduced escalation of care

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Optiflow Nasal High Flow
Recognize, stabalize, and mobilize graph

What clinical evidence is there, specific to the ED?

Reducing escalation in ED

Bell. 20151

Higher proportion of patients had > 20% reduction in respiratory rate using NHF: 66.7% NHF vs. 38.5% conventional oxygen therapy (COT), p=0.005.



Showed in an ED randomized control trial that NHF was associated with a lower proportion of patients requiring escalation in ventilation therapy.

Nasal high flow can decrease the need for escalation and might decrease the need for intubation.

(Meta-analysis; nasal high flow compared with COT and NIV)

- Huang, et al. Emerg Med Int. 2019.

“Patients with HFNC were much more likely to recover from respiratory failure.”

(Compared with COT in patients with acute hypoxemic respiratory failure)

- Mace, et al. Am J Emerg Med. 2019.

Optiflow in the ED: clinical studies summary

Emergency department clinical studies graph


Optiflow Adult Clinical Paper Summaries

(PDF 0.8MB)


Optiflow Newsletter - Issue 7

(PDF 0.0MB)


Optiflow Therapy Brochure

(PDF 0.9MB)



  1. Bell N, Hutchinson CL, Green TC, Rogan E, Bein KJ, Dinh MM. Randomised control trial of humidified high flow nasal cannulae versus standard oxygen in the emergency department. Emerg Med Australas. 2015;27(6):537–541
  1. Huang CC, Lan HM, Li CJ, et al. Use High-Flow Nasal Cannula for Acute Respiratory Failure Patients in the Emergency Department: A Meta-Analysis Study. Emerg Med Int. 2019;2019:2130935. Published 2019 Oct 13.
  1. Macé J, Marjanovic N, Faranpour F, et al. Early high-flow nasal cannula oxygen therapy in adults with acute hypoxemic respiratory failure in the ED: A before-after study. Am J Emerg Med. 2019;37(11):2091–2096.
  1. Lenglet H, Sztrymf B, Leroy C, Brun P, Dreyfuss D, Ricard JD. Humidified high flow nasal oxygen during respiratory failure in the emergency department: feasibility and efficacy. Respir Care. 2012;57(11):1873–1878.
  1. Jeong JH, Kim DH, Kim SC, et al. Changes in arterial blood gases after use of high-flow nasal cannula therapy in the ED. Am J Emerg Med. 2015;33(10):1344–1349.
  1. Makdee O, Monsomboon A, Surabenjawong U, et al. High-Flow Nasal Cannula Versus Conventional Oxygen Therapy in Emergency Department Patients With Cardiogenic Pulmonary Edema: A Randomized Controlled Trial. Ann Emerg Med. 2017;70(4):465–472.e2.
  1. Rittayamai N, Tscheikuna J, Praphruetkit N, Kijpinyochai S. Use of High-Flow Nasal Cannula for Acute Dyspnea and Hypoxemia in the Emergency Department. Respir Care. 2015;60(10):1377–1382.
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