Reducing patient escalation across
the care continuum.

Optiflow™ Nasal High Flow Therapy

Enquire about evaluating Optiflow Nasal High Flow
Optiflow™ Nasal High Flow at the Royal Berkshire Hospital

Introducing Optiflow to the Royal Berkshire Hospital - a multi-department implementation

Optiflow™ Nasal High Flow therapy at the Royal Berkshire Hospital. This video shows the usage of the F&P AIRVO™ 2 Humidified High Flow System & Optiflow Nasal High Flow therapy in different departments of the Royal Berkshire Hospital in Reading, UK. It shows the benefits they have found both to the patients and hospital since its introduction.

By clicking the play button on the video you are confirming that you are a healthcare professional
and entitled to watch this.

(3 minutes long)

Post-Extubation video

Extubation to Optiflow 

This video depicts extubation to Optiflow Nasal High Flow, and is based on the procedure used by Dr. Hernández and his colleagues' in the following studies:
1. Hernández et al. JAMA. 2016 (April) and
2. Hernández et al. JAMA. 2016 (Oct.) 

Using Optiflow to reduce the escalation of care for patients


While many acronyms have been used for this therapy, one name stands out as the way to deliver it: Optiflow HF.
Optiflow HF therapy from Fisher & Paykel Healthcare is at the forefront of the field, featuring in hundreds of publications and appearing in such prestigious journals as the NEJM and JAMA. Using Optiflow HF therapy as a first-line treatment (both pre-intubation and post-extubation) may reduce a patient’s escalation “up the acuity curve”, resulting in better patient outcomes and reduced costs of care.


“Use of NHF reduced the risk of reintubation within 72 hours.”

(among extubated patients at low risk of reintubation).

~ Hernández. et al. JAMA. Apr 2016.

“NHF significantly
reduced the need for intubation in more acute patients.”

(compared to standard O2 and NIV, PaO2:FiO2 ≤ 200 mmHg).

~ Frat et al. New Engl J Med. 2015.

“NHF was non-inferior to BPAP for treatment failure.”

(among extubated patients post cardiothoracic surgery).

~ Stéphan et al. JAMA. 2015.

Ready to evaluate Optiflow, in the ED, ICU or on a general floor?

Experience Optiflow HF therapy
in real patients, across the care continuum.

Make an evaluation enquiry and your local
Fisher & Paykel Healthcare representative
will arrange a visit to you and your team.

How does Optiflow work?

The mechanisms of action

With Optiflow HF therapy, you can independently titrate flow and FiO2 to match your patient’s needs. The mechanisms of action differ from those of conventional therapies, as do the resulting physiological effects and clinical outcomes.

The Optiflow HF therapy mechanisms of action are: 

  • Respiratory support (through the reduction of dead space
    and delivery of a dynamic positive airway pressure)
  • Airway hydration
  • Patient comfort
  • Supplemental oxygen (if required)

These mechanisms contribute to physiological effects such as reduced respiratory rate, improved oxygenation, reduced carbon dioxide levels, and improved mucus clearance.

Clinical studies suggest that Optiflow HF therapy may decrease the escalation of care, reduce mortality rates, and improve symptomatic relief.

Note: the above mechanisms of action for high flow apply to delivery through an Optiflow nasal cannula interface. The mechanisms of action differ when high flow is delivered through a tracheostomy or mask interface adapter.

Optiflow Mechanisms
Optiflow High Flow airway hydration mechanism overview
Airway hydration
Optiflow High Flow deadspace mechanism overview
Respiratory support
Optiflow High Flow pressure mechanism overview
Dynamic Positive Airway Pressure
Take me to FAQs


What about the economics -
does Optiflow make good financial sense?

Health systems worldwide are confronted by the need to reduce costs - or avoid them altogether.
The findings of recent Optiflow HF therapy studies, particularly those of Frat and Hernández, show that the use
of Optiflow HF both pre-intubation and post-extubation, may reduce escalation and avoid its associated costs.

Optiflow health economics graph

A patient’s journey through hospital may include periods of escalation and de-escalation of care.
Consider this conceptual model, above, showing two patients’ journeys through hospital.
The costs for these journeys are denoted by the areas of light blue and dark blue.

Flow Matters – Optiflow newsletter.

Keep up to date with the latest in Optiflow HF therapy clinical research.

Flow Matters - Issue 8

Flow Matters

Issue 8

Featured study: Ischaki et al. 2017
Focus: first published clinical protocol detailing the application of High Flow therapy for adult patients with acute hypoxemic respiratory failure.

Go With Flow - Issue 7

Go with the flow

Issue 7 

Featured study: Hernández et al. (Apr.) 2016
Focus: High Flow post-extubation to reduce the risk of reintubation.

Go With The Flow Issue 6

Go with the flow

Issue 6 

Featured studies:
1. Stéphan et al. 2015
2. Frat et al. 2015
Focus: High flow therapy compared with convetntional oxygen therapy and NIV.

Optiflow technology

Fisher & Paykel Healthcare technology was the first choice for the important studies published
in NEJM and JAMA, securing the place of Optiflow at the forefront of this exciting therapy.

Airvo™ 2 System

At a flow of 2 to 60 L/min, the AIRVO 2 is a standalone nasal high flow system can be used across the entire care continuum, from the ED and the ICU to the floors and in the home.

Optiflow™+ Nasal Cannula

The Optiflow + Nasal Cannula originated from Fisher & Paykel Healthcare's dedication to improve care and outcomes, giving clinicians confidence in the comfortable delivery of Nasal High Flow. 

MR850 System

The MR850 humidifier be used for the full range of Fisher & Paykel Healthcare therapies across the F&P Respiratory Care Continuum™.

Webinar focused on home use
of Nasal High Flow in patients
with chronic disease

Associate Professor Ulla Møller Weinreich speaks about
her research on humidified high flow therapy for patients
with chronic disease in this Nasal High Flow webinar.

Primary Outcome (intention to treat analysis)

Primary outcome of humidified high flow therapy for patients graph

Exacerbation rates (of chronic disease) were significantly lower in patients in the NHF + long term oxygen therapy (LTOT) group compared with the LTOT only group

Storgaard LH, Hockey HU, Laursen BS, Weinreich UM. Long–term effects of oxygen–enriched high–flow nasal cannula treatment in COPD patients with chronic hypoxemic respiratory failure. Int J Chron Obstruct Pulmon Dis. 2018; 13:1195–205.



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Using Optiflow to reduce the escalation of care for patients

  1. Frat JP, Thille AW, Mercat A, Girault C, Ragot S, Perbet S et al. High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure. N Engl J Med. 2015;372(23):2185–96.

How does Optiflow work?

Reduced respiratory rate
  1. Sztrymf B, Messika J, Bertrand F, Hurel D, Leon R, Dreyfuss D et al. Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study. Intensive Care Med. 2011; 37(11):1780–6.
  2. Corley A, Caruana LR, Barnett AG, Tronstad O, Fraser JF. Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients. Br J Anaesth. 2011; 107(6):998–1004.

What about the economics -
does Optiflow make good financial sense?

  1. Frat JP, Thille AW, Mercat A, Girault C, Ragot S, Perbet S et al. High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure. N Engl J Med. 2015;372(23):2185–96.