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Flow Matters

Keeping you up-to-date with emerging nasal high flow (NHF) clinical evidence and practice guidelines. 


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Evidence is published weekly demonstrating the impact of NHF on improved patient care and outcomes. More than 600 studies have alreay been published this year.*
Publications by year
(*updated Sept 2022)

pubmed.com - search term 'nasal high flow'
Registered clinical trials
(updated June 2022)

clinicaltrials.gov - search term 'nasal high flow'

Evidence-based clinical practice guidelines

New



Hundreds of randomized controlled trials have been consolidated into clinical practice guidelines. 

These guidelines underscore the breadth of application of nasal high flow therapy.

We’ve created a table that will help you review the  guidelines by patient population and application.

 

Interactive table 

NHF therapy in pediatric care

The use of NHF as a primary treatment for infants with bronchiolitis in the ED resulted in a significantly lower rate of therapy failure compared with standard oxygen therapy.
1 in 9 patients experienced therapy failure on
NHF 2 L/kg/min
1 in 4 patients experienced therapy failure on
standard O2 < 2 L/min

Updated Edition - October 2022


Early use of NHF in infants and children (new PICU study) 

In the PICU, the use of NHF as a primary treatment for acutely-ill children was non-inferior to CPAP, and resulted in lower use of sedation, nasal trauma and shorter durations of PICU and hospital stay.14

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Evidence-based guidelines recommend the use of NHF for COVID-19 patients 

Read about this and research related to airborne transmission.

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ROX Index - a bedside tool for monitoring patients on NHF

The validated ROX index uses just 3 data points to provide an indicator of outcomes in adults with AHRF receiving NHF therapy.


Author: Stanislav Taktov, M.D., Ph.D.

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